LGALS8, galectin 8, 3964

N. diseases: 51; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029453
Disease: Osteopenia
Osteopenia
0.020 Biomarker disease BEFREE Accordingly, the rate of bone loss is accelerated in ovariectomized, estrogen-deficient gal-8 Tg mice, whereas gal-8 KO mice, having low levels of ESR1, are refractory to ovariectomy. 29259034 2018
CUI: C0029453
Disease: Osteopenia
Osteopenia
0.020 Biomarker disease BEFREE Galectin-8 is a β-galactoside-recognising protein that has a role in the regulation of bone remodelling and is an emerging new target for tackling diseases with associated bone loss. 29926535 2018