LIPA, lipase A, lysosomal acid type, 3988

N. diseases: 130; N. variants: 50
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE We used the CESD-10 to measure depression and the PedsQL to measure psychosocial functioning, and used multilevel structural equation modeling to test hypotheses. 30656489 2020
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Based on the Chinese version of 10-item Center for Epidemiologic Studies Depression Scale (CESD-10), clinically relevant depressive symptoms were defined with a CESD-10 score≥10 points. 31744738 2020
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Of the respondents, 755 (372 males, 383 females; average age 14.26 years; SD 1.15) completed the 10-item Center for Epidemiological Studies Depression Scale (CESD-10). 29096523 2020
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Using a 2 × 2 MANOVA with depression (CESD ≥ 16) and apathy (AES ≥ 34) as the independent variables and cognitive performance (i.e., verbal acquisition, short-term free recall, and long-term free recall) as the dependent variables, we found a main effect for apathy (F[3,134] = 2.98, p = .034), such that apathetic stroke patients (n = 24) performed significantly worse on verbal acquisition (F[1,136] = 6.44; p = .012), short-term free recall (F[1,136] = 7.86; p = .006), and long-term free recall (F[1,136] = 8.37; p = .004) than nonapathetic stroke patients (n = 116). 29788381 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Of people who suspected depression (CESD-11>16), 32.6% experienced suicidal ideation, which is 12 times higher than that of total subjects. 31596870 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Using the Korean Longitudinal Study of Aging (KLoSA) database, Mini-Mental State Examination (MMSE) scores and Center for Epidemiologic Studies Depression Scale (CESD-10) indexes were used for measuring cognitive function and depression, respectively. 31817584 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Depressive symptoms (Centers for Epidemiologic Study of Depression [CESD]), quality of life (QoL), and clinical events (transplant-related hospitalization and death) were collected. 31518448 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE We also suggest a method to obtain the optimal cut-offs of SF-36 to predict depressive disorders.Key points• Both SF-36 MCS and SF-36 PCS were negatively correlated with K-CESD-R and K-POMS depression.• Patients with SF-36 MCS ≤ 48.07 exhibited a significantly high relative risk (RR) for depressive disorders, compared with those without (RR 42.667).• Patients with SF-36 PCS ≤ 55.63 showed a significantly high RR depressive disorder, compared with those without (RR 13.619). 31312987 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE The point prevalence of depression syndrome estimated by the CESD was higher than that estimated by the CIDI-SF (CESD: 9.9%-19.5% depending on the cutoff applied to the CESD vs CIDI-SF: 7.7%). 31112598 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE We used the data from the China Health and Retirement Longitudinal Study (CHARLS, 2013) (n = 10,935) This included data on financial transfers from all non-co-resident children to their parents, and the individual scores on depressive symptoms as measured by the 10-item Center for Epidemiologic Studies-Depression Scale (CESD-10). 30012123 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Therefore, the K-CESD-R Mobile app using algorithm (B) could be a more potential candidate for a depression screening tool than the K-CESD-R Mobile app using algorithm (A). 29944663 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Participants with complete data on religiosity (i.e., religious affiliation, frequency of attending religious activities and importance of religion), depression (assessed with the CESD-10), and trait anxiety (assessed with the STAI-10) were included in the present study. 29415030 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Over 12 years, mild and severe HL were associated with incident depression as assessed by the CESD in those without depression at baseline (OR = 1.36, 95% CIs 1.15-1.61; OR = 1.69, 95% CIs 1.15-2.30; respectively), but was not associated with a major depression diagnosis. 30209835 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Current depression was assessed with the Centre for Epidemiologic Studies Depression-8 (CESD-8). 28436695 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Multivariate linear regression analysis found that depressed mood (higher CESD-10 total scores) was significantly associated with ethnicity (Afro-Colombian), hot flush severity, hormone therapy use, sedentary lifestyle, postmenopause, perceived unhealthy status, and lower education. 28609394 2017