LIPA, lipase A, lysosomal acid type, 3988

N. diseases: 130; N. variants: 50
Disease: Cirrhosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1623038
Disease: Cirrhosis
Cirrhosis 		0.130 GeneticVariation disease BEFREE The median LAL was 0.36 (0.21-0.46)nmol/spot/h (vs. 0.29 (0.20-0.47); p = 0.558) for liver steatosis, 0.22 (0.11-0.29) nmol/spot/h (vs. 0.40 (0.34-0.51); p <0.001) for significant fibrosis and 0.21 (0.11-0.27) nmol/spot/h (vs. 0.40 (0.32-0.52); p < 0.001) for cirrhosis.No LIPA gene mutations were found. 31113613 2020
CUI: C1623038
Disease: Cirrhosis
Cirrhosis 		0.130 AlteredExpression disease BEFREE LAL-D is characterized by accelerated atherosclerotic cardiovascular disease (ASCVD) and hepatic microvesicular or mixed steatosis, leading to inflammation, fibrosis, cirrhosis and liver failure. 28197978 2017
CUI: C1623038
Disease: Cirrhosis
Cirrhosis 		0.130 Biomarker disease BEFREE Lysosomal Acid Lipase Activity Is Reduced Both in Cryptogenic Cirrhosis and in Cirrhosis of Known Etiology. 27219619 2016
CUI: C1623038
Disease: Cirrhosis
Cirrhosis 		0.130 Biomarker disease HPO