FADS1, fatty acid desaturase 1, 3992

N. diseases: 125; N. variants: 32
Disease: Coronary Arteriosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.040 GeneticVariation disease BEFREE Human genetic variants near the FADS (fatty acid desaturase) gene cluster (<i>FADS1-2</i>-<i>3</i>) are strongly associated with cardiometabolic traits including dyslipidemia, fatty liver, type 2 diabetes mellitus, and coronary artery disease. 29074585 2018
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.040 GeneticVariation disease BEFREE Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease. 27004414 2016
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.040 GeneticVariation disease BEFREE Dietary n-3 polyunsaturated fatty acid intakes modify the effect of genetic variation in fatty acid desaturase 1 on coronary artery disease. 25849351 2015
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.040 GeneticVariation disease BEFREE Fatty acid desaturase 1 polymorphisms are associated with coronary heart disease in a Chinese population. 22490578 2012