ASIC2, acid sensing ion channel subunit 2, 40

N. diseases: 33; N. variants: 4
Disease: Multiple Sclerosis ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.030 AlteredExpression disease BEFREE More importantly, analysis of human autoptic brain tissue in MS and control samples showed an increase of ASIC2 mRNA in MS samples. 30549327 2019
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.030 Biomarker disease BEFREE This is the case of amiloride-sensitive cation channel 1 neuronal (ACCN1) that shows a reduced number of interacting partners in MS networks, and it is known for its role in synaptic transmission and central nervous system (CNS) development. 27314336 2016
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.030 GeneticVariation disease BEFREE In the second stage of the study, we resequenced the exons and the 3' untranslated (UTR) region of ACCN1, and investigated the MS association of Single Nucleotide Polymorphisms (SNPs) identified in that region. 17534430 2007