LMNB1, lamin B1, 4001

N. diseases: 128; N. variants: 1
Disease: Muscle Rigidity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026837
Disease: Muscle Rigidity
Muscle Rigidity 		0.020 GeneticVariation phenotype BEFREE Conversely, treatment with histone demethylase inhibitors increases heterochromatin and chromatin nuclear rigidity, which results in reduced nuclear blebbing in lamin B1 null nuclei. 29142071 2018
CUI: C0026837
Disease: Muscle Rigidity
Muscle Rigidity 		0.020 AlteredExpression phenotype BEFREE Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts. 24858279 2014