DisGeNET - a database of gene-disease associations

LMO2, LIM domain only 2, 4005

N. diseases: 83; N. variants: 3

Disease: Adult Burkitt Lymphoma ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0278764
Disease:	Adult Burkitt Lymphoma

Adult Burkitt Lymphoma

0.030

Biomarker

disease

BEFREE

A combination of LMO2 negative and CD38 positive is useful for the diagnosis of Burkitt lymphoma.

31484540

2019

CUI:	C0278764
Disease:	Adult Burkitt Lymphoma

Adult Burkitt Lymphoma

0.030

Biomarker

disease

BEFREE

We also assess the utility of a germinal centre-associated marker, LMO2, in the differential diagnosis of BL in SE specimens.

30983044

2019

CUI:	C0278764
Disease:	Adult Burkitt Lymphoma

Adult Burkitt Lymphoma

0.030

GeneticVariation

disease

BEFREE

All BLs carried MYC translocation (P<0.001), whereas LMO2 was only positive in 6/42 (14%) LBCL with MYC translocation (P<0.001).

28288039

2017