LPA, lipoprotein(a), 4018

N. diseases: 340; N. variants: 49
Disease: Aortic valve disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1260873
Disease: Aortic valve disorder
Aortic valve disorder 		0.070 Biomarker disease BEFREE More recently, Lipoprotein(a) [Lp(a)] has been implicated as a key player in the pathogenesis of calcific aortic valve disease. 31150732 2019
CUI: C1260873
Disease: Aortic valve disorder
Aortic valve disorder 		0.070 Biomarker disease BEFREE This review summarizes recent findings of the roles played by ATX, LPA and LPA receptors (LPARs) in atherosclerosis and calcific aortic valve disease. 30928673 2019
CUI: C1260873
Disease: Aortic valve disorder
Aortic valve disorder 		0.070 GeneticVariation disease BEFREE Lipoprotein (a) [Lp(a)] has recently emerged as a causal, independent and genetic risk factor for cardiovascular disease and calcific aortic valve disease. 30986377 2019
CUI: C1260873
Disease: Aortic valve disorder
Aortic valve disorder 		0.070 GeneticVariation disease BEFREE Evidence continues to mount for an important role for elevated plasma concentrations of lipoprotein(a) [Lp(a)] in mediating risk of atherothrombotic and calcific aortic valve diseases. 29528858 2018
CUI: C1260873
Disease: Aortic valve disorder
Aortic valve disorder 		0.070 GeneticVariation disease BEFREE Lipoprotein(a) [Lp(a)] is an enigmatic lipoprotein which has been identified as a causal risk factor for coronary heart disease and calcific aortic valve disease. 29990619 2018
CUI: C1260873
Disease: Aortic valve disorder
Aortic valve disorder 		0.070 Biomarker disease BEFREE Evaluation of Lipoprotein(a) Electrophoretic and Immunoassay Methods in Discriminating Risk of Calcific Aortic Valve Disease and Incident Coronary Heart Disease: The Multi-Ethnic Study of Atherosclerosis. 28904058 2017
CUI: C1260873
Disease: Aortic valve disorder
Aortic valve disorder 		0.070 Biomarker disease BEFREE Lipoprotein (a) in calcific aortic valve disease: from genomics to novel drug target for aortic stenosis. 26685327 2016