LPL, lipoprotein lipase, 4023

N. diseases: 290; N. variants: 116
Disease: Hypotriglyceridemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0542037
Disease: Hypotriglyceridemia
Hypotriglyceridemia 		0.020 AlteredExpression disease BEFREE Mice expressing this transgene, denoted EC-hLpL and L for low and H for high expression, had decreased plasma TG levels compared with wild-type mice (WT): 106+/-31 in WT, 37+/-17 (line H), and 63+/-31 mg/dL (line L) because of a reduction in VLDL TG; plasma cholesterol and HDL levels were unaltered. 18258818 2008
CUI: C0542037
Disease: Hypotriglyceridemia
Hypotriglyceridemia 		0.020 AlteredExpression disease BEFREE Angptl3-deficient mice also displayed hypotriglyceridemia with elevated PHP LPL activity, but these mice showed a greater effect in the fed state. 16081640 2005