LRP1, LDL receptor related protein 1, 4035

N. diseases: 252; N. variants: 23
Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 Biomarker disease BEFREE Silencing of gp96 causes severe compromise in human multiple myeloma cell growth through inhibiting Wnt-LRP-survivin pathway. 24077352 2013
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 AlteredExpression disease BEFREE PRIMA-1Met/APR-246 displays high antitumor activity in multiple myeloma by induction of p73 and Noxa. 24030633 2013
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 AlteredExpression disease BEFREE Systematic analysis of expression of WNT, FZD, LRP and TCF gene families demonstrated that numerous Wnt-signalling components were expressed in human osteoclasts from patients with MM. 19961481 2010
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 AlteredExpression disease LHGDN IAP family protein expression correlates with poor outcome of multiple myeloma patients in association with chemotherapy-induced overexpression of multidrug resistance genes. 16929535 2006
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 Biomarker disease BEFREE MDR1, MRP1 and LRP have been identified as important adverse prognostic factors in AML, T-ALL and MM. 10809991 2000