LRP1, LDL receptor related protein 1, 4035

N. diseases: 252; N. variants: 23
Disease: Liposarcoma, Myxoid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206634
Disease: Liposarcoma, Myxoid
Liposarcoma, Myxoid 		0.020 GeneticVariation disease BEFREE Examination of myxoid liposarcomas and lipomas bearing the characteristic translocations (12;16)(q13;p11) or (12;variable)(q14;variable), respectively, excluded the breakpoints from within a 750-kb region surrounding the APR gene. 1318779 1992
CUI: C0206634
Disease: Liposarcoma, Myxoid
Liposarcoma, Myxoid 		0.020 AlteredExpression disease BEFREE Of particular interest is the frequent involvement of the 12q13-14 segment in clonal abnormalities in lipomas and myxoid liposarcomas, and it is possible that LRP may play a role in the pathogenesis of such tumors. 2548950 1989