LTA, lymphotoxin alpha, 4049

N. diseases: 353; N. variants: 26
Disease: Allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 Biomarker disease BEFREE The results indicate that LT-alpha-Ncol*1 may be a risk factor for atopic asthma in Taiwanese children. 18947013 2008
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 Biomarker disease BEFREE Both biochemical and genetic evidence have implicated the genes for TNF-alpha (TNFA) and lymphotoxin-alpha (LTA) in atopic asthma. 16728705 2006
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 GeneticVariation disease BEFREE Haplotype analysis of a 100 kb region spanning TNF-LTA identifies a polymorphism in the LTA promoter region that is associated with atopic asthma susceptibility in Japan. 15969671 2005
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 GeneticVariation disease BEFREE Gene-gene synergistic effect on atopic asthma: tumour necrosis factor-alpha-308 and lymphotoxin-alpha-NcoI in Taiwan's children. 14987295 2004
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.050 GeneticVariation disease BEFREE To determine whether polymorphisms in the 5' flanking region of the TNFA gene (-1031C/T, -863C/A, and -857C/T) and an NcoI polymorphism in the TNFB gene (LTA NcoI) are associated with the development of asthma, we performed transmission disequilibrium tests of families identified through children with atopic asthma. 12091169 2002