LTC4S, leukotriene C4 synthase, 4056

N. diseases: 50; N. variants: 3
Disease: Cerebrovascular accident ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.020 GeneticVariation group LHGDN Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations. 18323512 2008
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.020 GeneticVariation group BEFREE The previously observed association with the IL4R 503 S/P variant and the novel association with the LTC4S(-444) A/C variant suggest that these loci may also contribute to large vessel stroke risk in children with SCA. 17600229 2007