LTC4S, leukotriene C4 synthase, 4056

N. diseases: 50; N. variants: 3
Disease: IgE-mediated allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1827849
Disease: IgE-mediated allergic asthma
IgE-mediated allergic asthma 		0.020 GeneticVariation disease BEFREE This study supports the role of the LTC4S gene polymorphism in genetic susceptibility to atopic asthma in an Indian population. 22722751 2012
CUI: C1827849
Disease: IgE-mediated allergic asthma
IgE-mediated allergic asthma 		0.020 GeneticVariation disease BEFREE The -444A > C LTC4S polymorphism was significantly associated with NP and atopy (P = .033) and with NP and atopic asthma, (P =.012). 23101307 2012