SH2D1A, SH2 domain containing 1A, 4068

N. diseases: 160; N. variants: 8
Disease: Tuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 AlteredExpression disease BEFREE We previously demonstrated that Signaling lymphocytic activation molecule-associated protein (SAP) expression on cells from tuberculosis (TB) patients was inversely correlated with IFN-γ production. 28546549 2017
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 AlteredExpression disease BEFREE SAP proteins displayed increased expression when M. tuberculosis was resident within host cells, which may account in part for their ability to stimulate anti-M. tuberculosis host immunity. 23225904 2013
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker disease BEFREE The study further suggests that SAP and SLAM might be focal points for therapeutic modulation of T cell cytokine responses in tuberculosis. 14707094 2004
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 AlteredExpression disease LHGDN The study further suggests that SAP and SLAM might be focal points for therapeutic modulation of T cell cytokine responses in tuberculosis. 14707094 2004