MIRLET7D, microRNA let-7d, 406886

N. diseases: 82; N. variants: 1
Disease: LATERAL MENINGOCELE SYNDROME ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1851710
Disease: LATERAL MENINGOCELE SYNDROME
LATERAL MENINGOCELE SYNDROME 		0.010 Biomarker disease BEFREE Our findings showed that patients with <i>let-7e</i> downregulation had worse overall survival (OS) and is an independent prognostic factor (hazard ratio [HR] = 2.24<i>).</i> In addition, almost half the patients had distant metastasis<i>.</i> LMS patients with downregulated <i>let-7b</i> and <i>let-7d</i> had worse disease-free survival (DFS); they are not independent prognostic factors (HR = 2.65<i>).</i> Patients' ages were associated with <i>let-7d, let-7e</i> and <i>let-7f (p</i> = 0.0160<i>)</i> downregulation. 31744257 2019