MIR122, microRNA 122, 406906

N. diseases: 250; N. variants: 3
Disease: Fatty Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.060 Biomarker disease BEFREE These findings suggest miR-122 play important roles in goose fatty liver by targeting some of the genes related to lipid metabolism. 29182758 2018
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.060 AlteredExpression disease BEFREE Transgenic expression of MIR122 in hepatocytes of mice with ethanol-induced liver disease and advanced fibrosis significantly reduced serum levels of alanine aminotransferase (ALT) and liver steatosis and fibrosis, compared with mice given injections of the control vector. 28987423 2018
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.060 Biomarker disease BEFREE Are miRNA-103, miRNA-107 and miRNA-122 Involved in the Prevention of Liver Steatosis Induced by Resveratrol? 28375178 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.060 Biomarker disease BEFREE In conclusion, these results suggested that ACF may inhibit hepatic steatosis via miR‑122‑induced downregulation of FASN in vivo and in vitro. 27081834 2016
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.060 AlteredExpression disease BEFREE The serum level of miR-122 was correlated with the severity of liver steatosis. 23727030 2013
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.060 AlteredExpression disease BEFREE Inhibition of miR-122 with an antisense oligonucleotide results in decreased mRNA expression of lipogenic genes and improvement of liver steatosis. 23236228 2012