MIR122, microRNA 122, 406906

N. diseases: 250; N. variants: 3
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.080 AlteredExpression disease BEFREE These results reveal the serum exosomal miR-122-5p level is negatively associated with BAT activity independently of obesity. 31519959 2019
CUI: C0028754
Disease: Obesity
Obesity 		0.080 AlteredExpression disease BEFREE We identified four miRNAs overexpressed in obesity (miR-222, miR-142-3, miR-140-5p, and miR-143) and two miRNAs (miR-122 and miR-34a) overexpressed in children with obesity and nonalcoholic fatty liver disease (NAFLD) and/or insulin resistance. 31783635 2019
CUI: C0028754
Disease: Obesity
Obesity 		0.080 AlteredExpression disease BEFREE miR-155 and miR-122 Expression of Spermatozoa in Obese Subjects. 29896216 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE Both miR-378a and miR-122 were perturbed in metabolically relevant tissues in a murine model of obesity. 28834285 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE Circulating miR-122 was associated with prevalent insulin resistance, obesity, metabolic syndrome, type 2 diabetes, and an adverse lipid profile. 27899485 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE Mice overexpressing the longevity protein SIRT6 or deficient for the liver's most prevalent microRNA miR-122 display a similar set of phenotypes, including improved lipid profile and protection against damage linked to obesity. 26748705 2016
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE miR33a/miR33b* and miR122 as Possible Contributors to Hepatic Lipid Metabolism in Obese Women with Nonalcoholic Fatty Liver Disease. 27669236 2016
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE Elevated circulating miR-122 is positively associated with obesity and insulin resistance in young adults. 25515554 2015