|
Hepatitis C, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Elevated serum microRNA-122/222 levels are potential diagnostic biomarkers in Egyptian patients with chronic hepatitis C but not hepatic cancer.
|
26812693 |
2016 |
|
Hepatitis C, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Here, we report hepatic and serum miR-122 expression profiling from paired liver and serum samples from treatment-naive chronic hepatitis C (CHC) patients and controls.
|
26898400 |
2016 |
|
Hepatitis C, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Accordingly, patients with chronic hepatitis C and higher levels of hepatic miR-122 have lower hepatic expression of OCLN.
|
25302477 |
2015 |
|
Hepatitis C, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Circulating miRNA-122, miRNA-199a, and miRNA-16 as Biomarkers for Early Detection of Hepatocellular Carcinoma in Egyptian Patients with Chronic Hepatitis C Virus Infection.
|
26133725 |
2015 |
|
Hepatitis C, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our aims were to examine the associations between miR-122, apolipoproteins, and serum makers of fibrosis in chronic hepatitis C (CHC) patients.
|
25963774 |
2015 |
|
Hepatitis C, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, diagnostic potential of miR-122 is evaluated in the sera of chronic hepatitis C patients.
|
24696531 |
2014 |
|
Hepatitis C, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
IFNL3 (lambda-3 interferon gene) polymorphisms and the expression of miR-122 have been associated with sustained virological response (SVR) to treatment with pegylated interferon plus ribavirin in patients with chronic hepatitis C (CHC).
|
24672032 |
2014 |
|
Hepatitis C, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Miravirsen targets miR-122 and resulted in a dose dependent and prolonged decrease of HCV RNA levels in chronic hepatitis C patients.
|
25218783 |
2014 |
|
Hepatitis C, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Reduced levels of miR-122 in chronic hepatitis C thus appear to be associated with endogenous interferon responses to the virus, while differences in miR-122 expression in HCV- versus HBV-associated HCC likely reflect virus-specific mechanisms contributing to carcinogenesis.
|
24130799 |
2013 |
|
Hepatitis C, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our analysis of liver biopsies from subjects with chronic hepatitis C (CHC) undergoing IFN therapy revealed no correlation of miR-122 expression with viral load and markedly decreased pretreatment miR-122 levels in subjects who had no virological response during later IFN therapy; other investigated miRNAs showed only limited changes.
|
19122656 |
2009 |