MIR125B2, microRNA 125b-2, 406912

N. diseases: 38; N. variants: 0
Disease: Down Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.320 Biomarker disease CTD_human A number of miRNAs are overexpressed in down syndrome, including miR-155, miR-802, miR- 125b-2, let-7c and miR-99a. 29403643 2018
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.320 AlteredExpression disease BEFREE Recently, the over expression of chromosome 21-derived microRNAs (miR-99a, let-7c, miR-125b-2, miR-155 and miR-802) in human fetal hippocampus and heart samples from individuals with Down syndrome was observed. 24521639 2013
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.320 Biomarker disease BEFREE Thus, we propose miR-125b-2 as a positive regulator of megakaryopoiesis and an oncomiR involved in the pathogenesis of trisomy 21-associated megakaryoblastic leukemia. 20194440 2010