MIR140, microRNA 140, 406932

N. diseases: 144; N. variants: 2
Disease: Squamous cell carcinoma of tongue ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0349566
Disease: Squamous cell carcinoma of tongue
Squamous cell carcinoma of tongue 		0.020 AlteredExpression disease BEFREE The expression of <i>MALAT1</i> and p21 (RAC1)-activated kinase 1 (PAK1) was upregulated and microRNA-140-5p (<i>miR-140-5p</i>) expression was downregulated in TSCC tissues and cells. 30863103 2019
CUI: C0349566
Disease: Squamous cell carcinoma of tongue
Squamous cell carcinoma of tongue 		0.020 Biomarker disease BEFREE Taken together, our results suggest that miR-140-5p play a role in TSCC cell migration and invasion, and two brand new relationships between miRNA and its targets emerged: (1) ADAM10 is not just a direct target of miR-140-5p, the repressed ADAM10 also helps to enhance the effect of miR-140-5p to other target genes: ERBB4 and PAX6; (2) ERBB4 is "positively" regulated by miR-140-5p. 24530397 2014