MIR141, microRNA 141, 406933

N. diseases: 179; N. variants: 0
Disease: Hirschsprung Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019569
Disease: Hirschsprung Disease
Hirschsprung Disease 		0.020 Biomarker disease BEFREE Two key miRNAs (miR-141-3p and miR-30a-3p), the MAPK signaling pathway and two key genes (FZD3 and DOK6) were implicated in the pathogenesis of HSCR. 28965333 2017
CUI: C0019569
Disease: Hirschsprung Disease
Hirschsprung Disease 		0.020 AlteredExpression disease BEFREE MiR-141 was down-regulated whereas CD47 and CUL3 expression was increased in colon tissues from patients with HSCR compared with control group, The increased level of CD47 and CUL3 induced by miR-141 reduced proliferation and migration of 293T and SH-SY5Y cells. 24334875 2013