MIR141, microRNA 141, 406933

N. diseases: 179; N. variants: 0
Disease: Autoimmune myocarditis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1608389
Disease: Autoimmune myocarditis
Autoimmune myocarditis 		0.010 Biomarker disease BEFREE Taken together, upregulation of miR-141-3p alleviates the inflammatory response in EAM mice by inhibiting STAT4, providing a promising intervention target for the molecular treatment of AM.<b>NEW & NOTEWORTHY</b> miR-141-3p is poorly expressed, and STAT4 is upregulated in experimental autoimmune myocarditis (EAM) mice.Overexpressing miR-141-3p inhibits EAM. miR-141-3p binds to and suppresses STAT4 expression. miR-141-3p overexpression inhibits inflammatory factors by downregulating STAT4. 31225989 2019