MIR146A, microRNA 146a, 406938

N. diseases: 505; N. variants: 3
Disease: Muscle damage ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0410158
Disease: Muscle damage
Muscle damage 		0.010 Biomarker phenotype BEFREE However, muscle degeneration was not significantly worsened in mdx mice lacking miR-146a up to 24 weeks of age, although some aggravation of muscle damage and inflammation was evident in 12-week-old animals, though no effect of miR-146a deficiency was visible on quantity, proliferation, and in vitro differentiation of muscle satellite cells isolated from miR-146a<sup>-/-</sup>mdx mice vs. mdx. 31412923 2019