MIR146A, microRNA 146a, 406938

N. diseases: 505; N. variants: 3
Disease: Acute Chest Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.040 Biomarker disease BEFREE In this case-control study, we explored the role of the inflammatory microRNA, miR-146a, in acute coronary syndrome (ACS) subjects with and without chronic periodontitis (CP) and its regulation of the innate immune host response to periodontal pathogens. 30618100 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.040 AlteredExpression disease BEFREE MiR-223, miR-92a, miR-486, miR-122, miR-125a and miR-146a levels were higher in the hyperglycemic ACS compared to normoglycemic sera. 27519051 2016
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.040 GeneticVariation disease BEFREE In summary, this study provides the first evidence that the CG genotype of miR-146a rs2910164 is associated with a significantly decreased risk of ACS in a Chinese population. 26537765 2015
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.040 Biomarker disease BEFREE The results support the concept that miR-146a may be a novel regulatory factor in Th1 differentiation and a new therapeutic target for AS and ACS. 20195282 2010