MIR150, microRNA 150, 406942

N. diseases: 282; N. variants: 0
Disease: Osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker disease BEFREE These findings indicate that MIAT functions by competing with critical RNAs to target miR-150-5p and activate zinc finger E-box binding homeobox 1 to modulate the function of osteosarcoma cells. 30655889 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 AlteredExpression disease BEFREE As a result, miR-150 expression was significantly decreased, while IGF2BP1 mRNA and protein expression were dramatically increased in osteosarcoma tissues compared to matched adjacent noncancerous tissues (all P < 0.001). 30220021 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 AlteredExpression disease BEFREE Secondly, it was shown that the overexpression of miR-150 was inversely correlated with OS cell proliferation, migration and invasion. 28454380 2017
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker disease BEFREE In conclusion, miR-150 targeted ZEB1 to function as an antioncogenic regulator in OS. 28781686 2017
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 AlteredExpression disease BEFREE Ectopic overexpression of miR-150 inhibited osteosarcoma cell 28547952 2017
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker disease BEFREE Taken together, these findings suggest that miR-150 functions as a tumor suppressor in OS partially by targeting IGF2BP1. 26561465 2016
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker disease BEFREE MicroRNA-150 Inhibits Cell Invasion and Migration and Is Downregulated in Human Osteosarcoma. 26361218 2015