Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Correction to: BRG1 regulation by miR-155 in human leukemia and lymphoma cell lines.
|
31350682 |
2019 |
Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Moreover, miR155 enhanced lymphoma cell PD-L1 expression, recruited CD8+T cells by PD-1/PD-L1 interaction and inhibited CD8+T cell function via dephosphorylating AKT and ERK.
|
30925928 |
2019 |
Adult Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
miR-155, a microRNA associated with poor prognosis in lymphoma and leukaemia, has been implicated in the progression of mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL).
|
30125933 |
2018 |
Adult Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
These results indicated that LMP1 and miR-155 may be novel and reliable biomarkers for the prognostic prediction of lymphoma, and will potentially be analyzed in the future to evaluate patient prognosis.
|
29844839 |
2018 |
Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
SOCS3 reduction and miR-155 up-regulation are associated with lymphoma pathogenesis.
|
29228427 |
2017 |
Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Downregulation of miR-155 inhibited lymphoma cell progress by arresting cell cycle in the G0/G1 phase and promoting apoptosis.
|
28281962 |
2016 |
Adult Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
A number of studies have shown that miR-155 can not only regulate cell proliferation, apoptosis and lymphoma progression, but also plays an important part in various other physiological and pathological processes.
|
26072128 |
2015 |
Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Subsequent studies have shown that transgenic mice expressing miR-155 in B cells generated lymphoma, showing that miR-155 is oncogenic.
|
25829072 |
2015 |
Adult Lymphoma
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
To test if methylation of miR-155-3p was MCL-specific, miR-155-3p methylation was tested in an additional 191 B-cell, T-cell and NK-cell NHLs, yielding miR-155-3p methylation in 66(34.6%) including 36(27%) non-MCL B-cell, 24(53%) T-cell and 6(46%) of NK-cell lymphoma.
|
25211095 |
2014 |
Adult Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
But only microRNA-155 was significantly higher in the uveitic vitreous compared to that with lymphoma.
|
24345320 |
2014 |
Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
High levels of miR-155 have been detected in human neoplasms, and overexpression of miR-155 has been found to induce lymphoma in mice.
|
23750211 |
2013 |
Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, this effect may contribute to lymphoma cell dissemination and aggressiveness, characteristic of activated B cell-like diffuse large B-cell lymphoma typically expressing high levels of miR-155 and lacking HGAL expression.
|
22096245 |
2012 |
Adult Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Collectively, these results provide important new insight into the pathogenesis of NK-cell lymphoma/leukemia and suggest targeting miR-21 and/or miR-155 may represent a useful approach to treating NK-cell lymphoma/leukemia.
|
19641183 |
2009 |
Adult Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
As compared to LN, some miRNAs are differentially regulated in both lymphoma types (MIRN155, MIRN210, MIRN106A, MIRN149 and MIRN139).
|
18537969 |
2008 |