MIR186, microRNA 186, 406962

N. diseases: 105; N. variants: 1
Disease: Osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.040 Biomarker disease BEFREE In addition, our studies showed that miR-186-5p was a downstream target of NEAT1 in OS. 30485482 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.040 Biomarker disease BEFREE However, the detailed molecular mechanisms underlying miR-186-5p-involved osteosarcoma are unclear. 30897321 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.040 Biomarker disease BEFREE Among the target genes of miR‑186, we found that pituitary tumor transforming gene 1 (PTTG1) may be a target gene of miR‑186 in OS and that the overexpression of PTTG1 could partially abolish miR‑186‑mediated suppressive effects on OS cells. 29693191 2018
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.040 Biomarker disease BEFREE Taken together, miR-186-5p/TBL1XR1 may be a novel therapeutic candidate target in osteosarcoma treatment. 30662805 2018