MIR21, microRNA 21, 406991

N. diseases: 726; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3146257
Disease: Stage II Colon Cancer AJCC v7
Stage II Colon Cancer AJCC v7
0.030 Biomarker disease BEFREE This population-based study supports miRNA-21 as an additional prognostic biomarker in patients with stage II colon cancer. 25051407 2014
CUI: C3146257
Disease: Stage II Colon Cancer AJCC v7
Stage II Colon Cancer AJCC v7
0.030 Biomarker disease BEFREE Further investigations of the clinical importance of miR-21 in the selection of high-risk stage II colon cancer patients are merited. 23011541 2012
CUI: C3146257
Disease: Stage II Colon Cancer AJCC v7
Stage II Colon Cancer AJCC v7
0.030 AlteredExpression disease BEFREE High TBR (and TB) estimates of miR-21 expression correlated significantly with shorter disease-free survival (p = 0.004, HR = 1.28, 95% CI: 1.06-1.55) in the stage II colon cancer patient group, whereas no significant correlation with disease-free survival was observed in the stage II rectal cancer group. 21069438 2011