MIR221, microRNA 221, 407006

N. diseases: 288; N. variants: 2
Disease: Mammary Neoplasms ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.350 AlteredExpression group BEFREE Profiling the predicted E-cadherin-targeting miRNAs in breast cancer tissues and cells showed that miR-221 was abundantly expressed in breast tumor and metastatic MDA-MB-231 cells and its level was significantly higher in breast tumor or MDA-MB-231 cells than in distal non-tumor tissue and low-metastatic MCF-7 cells, respectively. 27174021 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.350 Biomarker group BEFREE Importantly, this 14-3-3ζ-miR-221-p27 proliferation axis is also functioning in breast tumors in patients and is associated with high-grade cancers. 24197133 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.350 AlteredExpression group BEFREE We present a link between β4 integrin expression and miR-221/222 in the most prevalent human mammary tumor: luminal invasive carcinomas (Lum-ICs). 24736554 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.350 AlteredExpression group BEFREE We have shown earlier that miR-221 and -222 are up-regulated in tamoxifen-resistant MCF-7 (OHT(R)) cells and Her2-positive human breast tumors when compared with Her2 negative tumors. 22009755 2011