MIR29A, microRNA 29a, 407021

N. diseases: 278; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.030 AlteredExpression disease BEFREE Interestingly, IL-21 upregulation correlated with a significantly increased expression of miR-29a,b,c and a reduced susceptibility to in-vitro HIV-1 infection in HESN alone. 30005016 2018
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.030 AlteredExpression disease BEFREE Of these, both miR-26a and miR-29a were downregulated in untreated HIV-1 infection, yet not in the colonic mucosa from inflammatory bowel disease. 28692540 2017
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.030 Biomarker disease BEFREE Together, these findings reveal a novel antiviral IL-21-miR-29 axis that promotes CD4 T-cell-intrinsic resistance to HIV-1 infection, and suggest a role for IL-21 in initial HIV-1 control in vivo. 26108174 2015