MIR30E, microRNA 30e, 407034

N. diseases: 88; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 AlteredExpression phenotype BEFREE In NSCLC cell lines, enforced expression of miR-30e could inhibit cell proliferation and invasion in vitro. 31079325 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 Biomarker phenotype BEFREE Thus, the aim of the present study was to investigate the effects of miR‑30e and its target gene, M3 muscarinic acetylcholine receptor (CHRM3), on the adhesion, migration, invasion and cell cycle distribution of PCa cells via the mitogen‑activated protein kinase (MAPK) signaling pathway. 30483762 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 AlteredExpression phenotype BEFREE MiR-30e overexpression suppressed cell invasion and migration via inhibiting EMT, whereas miR-30e inhibition promoted EMT, cell invasion and migration. 29662654 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 AlteredExpression phenotype BEFREE The results revealed that overexpression of miR-30e-3p in the A498 and 786O ccRCC cell lines was able to inhibit cell invasion and migration. 28454361 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 AlteredExpression phenotype BEFREE In this study, we found that miR-30e was significantly downregulated in tumor tissues of breast cancer (BC) patients and cell lines, and overexpression of miR-30e inhibited cell proliferation, migration and invasion. 29162879 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.060 AlteredExpression phenotype BEFREE Knocking down CBL-B expression phenocopied the effects of miR-30e, whereas ectopic expression of CBL-B suppressed miR-30e-induced EGFR up-regulation and invasion. 25691332 2015