Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 Biomarker group BEFREE The MARCKS-ED-photodoxaz system targeting exosomes and utilizing photochemistry will potentially provide a new approach for the treatment of cancer, especially for highly progressive and invasive metastatic cancers. 30703330 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 AlteredExpression group BEFREE We compared MARCKS expression in normal versus cancer samples, and searched for correlations with clinicopathological features, including overall survival (OS). 29295532 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 AlteredExpression group BEFREE These data suggested that miR‑34c‑3p acts as a tumor suppressor via regulation of MARCKS expression in OS progression and miR‑34c‑3p may be a promising therapeutic target for this type of cancer. 28075441 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 Biomarker group BEFREE MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis. 27081703 2016
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 Biomarker group BEFREE Since the MARCKS function depends on its phosphorylation status, which impacts its subcellular location, MARCKS role in cancer may depend highly on the signaling context. 25524703 2015
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 PosttranslationalModification group BEFREE However, the functionality of MARCKS and its related phosphorylation in lung cancer malignancy have not been characterized. 23955080 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 Biomarker group BEFREE Elucidation of mechanisms that promote EGFRvIII-mediated tumorigenesis in GBM, such as MARCKS, provides additional understanding and potential biological targets against this currently terminal human cancer. 19773446 2009
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.080 PosttranslationalModification group BEFREE We also analyzed the change of MARCKS localization on the influence of MARCKS phosphorylation in the HLF cancer cell line by phosphorylation study. 15703821 2005