SMAD4, SMAD family member 4, 4089

N. diseases: 575; N. variants: 144
Disease: Pancreatic Intraductal Papillary Mucinous Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4511687
Disease: Pancreatic Intraductal Papillary Mucinous Neoplasm
Pancreatic Intraductal Papillary Mucinous Neoplasm 		0.030 AlteredExpression disease BEFREE Interestingly, decreased WWOX expression was significantly correlated with loss of SMAD4 expression in these IPMNs. 19352382 2009
CUI: C4511687
Disease: Pancreatic Intraductal Papillary Mucinous Neoplasm
Pancreatic Intraductal Papillary Mucinous Neoplasm 		0.030 Biomarker disease BEFREE The protein expression of p53, p21(WAF1/CIP1), cyclin D1, p16(INK4A) and DPC4/Smad4 were examined by immunohistochemistry in 267 PanIN lesions from a cohort of 23 patients with IPMN. 15316318 2004
CUI: C4511687
Disease: Pancreatic Intraductal Papillary Mucinous Neoplasm
Pancreatic Intraductal Papillary Mucinous Neoplasm 		0.030 AlteredExpression disease BEFREE Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: comparison with conventional ductal adenocarcinomas. 10980115 2000