SMAD7, SMAD family member 7, 4092

N. diseases: 269; N. variants: 21
Disease: Echinococcus multilocularis infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0152069
Disease: Echinococcus multilocularis infection
Echinococcus multilocularis infection 		0.010 AlteredExpression disease BEFREE The time course of the various actors of the TGF-β/Smad system in the in vivo mouse model as well as down-regulation of Smad7 in liver areas close to the lesions in human cases highly suggest that TGF-β plays an important role in AE both in immune tolerance against the parasite and in liver fibrosis. 23405141 2013