SMAD7, SMAD family member 7, 4092

N. diseases: 269; N. variants: 21
Disease: Skin Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519346
Disease: Skin Carcinogenesis
Skin Carcinogenesis 		0.020 Biomarker disease BEFREE Smad7 Ameliorates TGF-β-Mediated Skin Inflammation and Associated Wound Healing Defects but Not Susceptibility to Experimental Skin Carcinogenesis. 30423327 2019
CUI: C1519346
Disease: Skin Carcinogenesis
Skin Carcinogenesis 		0.020 Biomarker disease BEFREE Taken together, these data support a novel role for SMAD7 as a tumor promoter in skin carcinogenesis where SMAD7 stimulates the DNA repair pathway and EGFR signaling activation. 30219864 2019