Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms in genes coding for the serotonin receptor subtype 1A (HTR1A), the serotonin transporter (SLC6A4), and the serotonin degrading enzyme monoamine oxidase A (MAOA) are associated with anxiety, impulsivity, and neurotic personality in humans.
|
31045220 |
2019 |
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
In fact, MAOA-uVNTR and trait anxiety also explained emotional stability and its subdimensions.
|
31448578 |
2019 |
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Monoamine oxidase A (MAO-A) plays an important role in various functions of the brain, such as regulation of mood, anxiety and aggression, and dysregulation of MAO-A is observed in stress-related psychiatric disorders.
|
30687104 |
2018 |
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Perseveration in a spatial-discrimination serial reversal learning task is differentially affected by MAO-A and MAO-B inhibition and associated with reduced anxiety and peripheral serotonin levels.
|
28251298 |
2017 |
Anxiety
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Burned mice showed "delayed" depressive-like behavior combined with a degree of anxiety; this phenomenon is likely associated with the increase in MAOA expression in the hippocampus.
|
28413107 |
2017 |
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The study did not demonstrate the relationship between the 5-HTT and MAO-A gene polymorphisms, and the severity of anxiety and mood disorders in healthy late-reproductive-stage women.
|
27614969 |
2016 |
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study supports a potential therapeutic use for MAO-A inhibitors in the treatment of depression and anxiety in patients with HD.
|
26825854 |
2016 |
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our findings support a possible association, depending on gender, between the MAOA-uVNTR polymorphism and psychopathological disorders such as anxiety, which affects high rates of children and adolescents.
|
25747527 |
2015 |
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, the analysis of the 30-bp VNTR polymorphism in the MAO A promoter region demonstrated slight differences in anxiety levels between the women, indicating that those with a 4/4 genotype had higher severity of anxiety symptoms.
|
25547397 |
2014 |
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The relationship between MAOA gene polymorphism and test anxiety.
|
24229476 |
2013 |
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
In boys, low-activity monoamine oxidase A gene was associated with increases in child anxiety and depression in interaction with caretaker depression, hostility, family conflict, and family stress.
|
23627963 |
2013 |
Anxiety
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The current study aimed to determine whether maternal symptoms of depression or anxiety were associated with decreased placental expression of monoamine oxidase A (MAO A), the enzyme which metabolises 5-HT into 5-hydroxyindoleacetic acid.
|
24119940 |
2013 |
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Therefore, the aim of this study was to examine gene-by-environment interactions of the genes coding for catechol-O-methyltransferase (COMT) and monoamine oxidase A (MAOA) with life events on measures related to anxiety.
|
24118915 |
2013 |
Anxiety
|
0.100 |
Biomarker
|
disease |
BEFREE |
Indeed, treating animals with MAO-A inhibitors or selective serotonin reuptake inhibitors (SSRIs) normalized anxiety differences between wild-type and mutant animals.
|
22169038 |
2011 |
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of a monoamine oxidase-a gene promoter polymorphism with ADHD and anxiety in boys with autism spectrum disorder.
|
18566880 |
2009 |
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Because fibromyalgia (FM) is often comorbid with anxiety, and monoamine oxidase A (MAOA) was reported to be associated with anxiety, we determine if there is MAOA gene polymorphism associated with FM patients.
|
16547693 |
2007 |
Anxiety
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our findings further support the notion that allelic variation of MAOA activity contributes modestly to the balance of hyper- (impulsive-aggressive) and hyporeactive (anxious-depressive) traits.
|
15870836 |
2005 |
Anxiety
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A SERT gene genotype with no apparent individual effect on risk and known to be associated with anxiety is preferentially transmitted to children with AN (chi2 trend=9.457, 1 df, P=0.0021) and AN-R alone (chi2 trend=7.477, 1 df, P=0.0063) when the 'more active' MAOA gene variant is also transmitted.
|
15523490 |
2005 |