MAOA, monoamine oxidase A, 4128

N. diseases: 300; N. variants: 15
Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.010 Biomarker disease BEFREE However, EN-460 was also found to inhibit other FAD-containing enzymes including MAO-A (IC<sub>50</sub> = 7.91 μM), MAO-B (IC<sub>50</sub> = 30.59 μM) and LSD1 (IC<sub>50</sub> = 4.16 μM), suggesting overlap in inhibitor activity and the potential need to develop more specific inhibitors to enable pharmacological validation of ERO1L as a target for the treatment of MM. 30850265 2019