MAOB, monoamine oxidase B, 4129

N. diseases: 152; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior
0.020 AlteredExpression phenotype BEFREE The role of MAOB in behavioral regulation remains less well-understood, even though Maob-deficient mice have been found to exhibit greater behavioral disinhibition and risk-taking responses, supporting previous clinical studies showing associations between low MAO B activity and impulsivity. 29748850 2018
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior
0.020 GeneticVariation phenotype BEFREE Most of the studies converge in associating MAO-A and MAO-B with impulsive, aggressive or antisocial personality traits or behaviours, including alcohol-related problems, and for MAO-A available evidence strongly supports interaction with adverse environmental exposures in childhood. 26964906 2016