MAP2, microtubule associated protein 2, 4133

N. diseases: 126; N. variants: 3
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.040 AlteredExpression disease BEFREE Because MAP2 promoter activity levels in melanoma cell lines also correlated with activating mutation in BRAF, a gene that is highly expressed in neurons, we hypothesized that BRAF signaling is involved in MAP2 expression. 19880519 2010
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Our results suggest that MAP2 may serve as a promising molecular target for therapy and chemoprevention of MM in humans. 20100193 2010
CUI: C0025202
Disease: melanoma
melanoma 		0.040 AlteredExpression disease BEFREE We showed that MAP2 is frequently activated in human cutaneous melanoma. 16916793 2006
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease LHGDN We showed that MAP2 is frequently activated in human cutaneous melanoma. 16916793 2006
CUI: C0025202
Disease: melanoma
melanoma 		0.040 AlteredExpression disease BEFREE Immunohistochemical analysis of 61 benign and malignant melanocytic lesions showed abundant expression of MAP-2 protein in melanocytic nevi and in the in situ and invasive components of primary melanoma, but only focal heterogeneous expression in a few metastatic melanomas. 11395388 2001