MAPT, microtubule associated protein tau, 4137

N. diseases: 469; N. variants: 292
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.060 Biomarker disease BEFREE The serum level of tau protein is lower in MS and it may be considered as a potential biomarker in Multiple sclerosis. 31733529 2020
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.060 GeneticVariation disease BEFREE Further studies might also focus on the trafficking along microtubules in neurons of MS patient with regard to hyperphosphorylation of tau protein. 27697018 2018
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.060 Biomarker disease BEFREE Simultaneous quantification of Myelin Basic Protein and Tau proteins in cerebrospinal fluid and serum of Multiple Sclerosis patients using nanoimmunosensor. 27816592 2017
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.060 Biomarker disease BEFREE We previously reported hyperphosphorylated and aggregated microtubule-associated protein tau in MS lesions, suggesting its involvement in axonal degeneration. 26576485 2016
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.060 GeneticVariation disease BEFREE These results suggest that MAPT rs1052553 polymorphism is not related with the risk for relapsing bout onset MS. 23911736 2013
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.060 AlteredExpression disease LHGDN In MS patients levels of tau protein were positively correlated with the IgG index (p<0.05) and this association was present in both relapsing remitting MS (RRMS) (p<0.05) and progressive MS (p<0.05). 15083285 2004