Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020545
Disease: Hypertension, Renovascular
Hypertension, Renovascular
0.020 Biomarker disease BEFREE Very few studies investigated the role of components of the counterregulatory RAS axis (ACE2, Ang-(1-7) and Mas receptor) in renovascular hypertension and the results are controversial. 30950337 2019
CUI: C0020545
Disease: Hypertension, Renovascular
Hypertension, Renovascular
0.020 Biomarker disease BEFREE An increase in the intratubular nonclassic RAS [ACE2/angiotensin (1-7)/Mas receptor] and a decrease in the ANG II type 1-to-type 2 receptor ratio could limit the adverse effects of the classic RAS during renovascular hypertension in female rats, and estrogen is suggested to play a primary role in the regulation of intratubular RAS components. 31339773 2019