Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.020 Biomarker group BEFREE Nevertheless, novel drugs are now aimed at the brain RAS, i.e., aminopeptidase A inhibitors should block Ang III formation from Ang II, and hence diminish AT<sub>1</sub> receptor stimulation by Ang III, while AT<sub>2</sub> and Mas receptor agonists are reported to induce neuroprotection after stroke. 30949864 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.020 Biomarker group BEFREE The counter-regulatory axis, Angiotensin Converting Enzyme 2, Angiotensin-(1-7), Mas receptor (ACE2/Ang-1-7/MasR), of the renin angiotensin system (RAS) is a potential therapeutic target in stroke, with Ang-(1-7) reported to have neuroprotective effects in pre-clinical stroke models. 30816157 2019