|
Neoplasms
|
0.090 |
AlteredExpression
|
group |
BEFREE |
PIM3 was found to be expressed in a panel of human Ewing's family tumor cell lines.
|
12748291 |
2003 |
|
Pancreatic carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines.
|
16818649 |
2006 |
|
Malignant neoplasm of pancreas
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines.
|
16818649 |
2006 |
|
Liver carcinoma
|
0.090 |
Biomarker
|
disease |
BEFREE |
Pim-3 transgenic mice developed HCC with a higher incidence (80%) and a heavier burden, together with enhanced intratumoral CD31-positive vascular areas, compared with that observed for wild-type mice.
|
20101231 |
2010 |
|
Liver Failure, Acute
|
0.020 |
Biomarker
|
disease |
BEFREE |
PIM3 is a prime candidate gene for the fulminant hepatic failure in the two patients; SHANK3/PROSAP2 could be another candidate gene.
|
20635403 |
2010 |
|
leukemia
|
0.050 |
Biomarker
|
disease |
BEFREE |
Pim-3 is a member of the Provirus integrating site Moloney murine leukemia virus (Pim) family, which belongs to the Ca(2+) /calmodulin-dependent protein kinase (CaMK) group and exhibits serine/threonine kinase activity.
|
21518143 |
2011 |
|
Childhood Leukemia
|
0.050 |
Biomarker
|
disease |
BEFREE |
Pim-3 is a member of the Provirus integrating site Moloney murine leukemia virus (Pim) family, which belongs to the Ca(2+) /calmodulin-dependent protein kinase (CaMK) group and exhibits serine/threonine kinase activity.
|
21518143 |
2011 |
|
Pancreatic carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Pim-3 promotes human pancreatic cancer growth by regulating tumor vasculogenesis.
|
24789328 |
2014 |
|
Malignant neoplasm of pancreas
|
0.100 |
Biomarker
|
disease |
BEFREE |
Pim-3 promotes human pancreatic cancer growth by regulating tumor vasculogenesis.
|
24789328 |
2014 |
|
Pancreatic carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Pim-3 could promote growth and angiogenesis of human pancreatic cancer cells in vivo in an orthotopic nude mouse model.
|
25071334 |
2014 |
|
Malignant neoplasm of pancreas
|
0.100 |
Biomarker
|
disease |
BEFREE |
Pim-3 could promote growth and angiogenesis of human pancreatic cancer cells in vivo in an orthotopic nude mouse model.
|
25071334 |
2014 |
|
Pancreatic carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Pim-3 expression was a prognostic indicator related to poor survival in pancreatic cancer patients.
|
25971209 |
2015 |
|
Malignant neoplasm of pancreas
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Pim-3 expression was a prognostic indicator related to poor survival in pancreatic cancer patients.
|
25971209 |
2015 |
|
Secondary malignant neoplasm of liver
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Pim-3 expression showed a positive correlation with tumor cell differentiation, local infiltration, and lymph node and liver metastasis.
|
26768612 |
2016 |
|
Leukemia, T-Cell
|
0.010 |
Biomarker
|
disease |
BEFREE |
Pim-3 is a potentially suitable target for the development of novel therapeutic agents against ATL.
|
28833639 |
2017 |
|
Adult T-Cell Lymphoma/Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Pim-3 is a potentially suitable target for the development of novel therapeutic agents against ATL.
|
28833639 |
2017 |
|
leukemia
|
0.050 |
Biomarker
|
disease |
BEFREE |
Pim-3 is a member of the provirus integration site for a moloney murine leukemia virus family of proteins that contributes to cell proliferation, survival, and chemotherapy resistance.
|
29167471 |
2017 |
|
Childhood Leukemia
|
0.050 |
Biomarker
|
disease |
BEFREE |
Pim-3 is a member of the provirus integration site for a moloney murine leukemia virus family of proteins that contributes to cell proliferation, survival, and chemotherapy resistance.
|
29167471 |
2017 |
|
Rectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Pim-3 is a potential predictive biomarker for the response of rectal cancer to chemoradiotherapy.
|
29167471 |
2017 |
|
Tumor Progression
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
Pim-3, a highly expressed oncogene in melanoma, is a highly conserved serine/threonine kinase with various biological activities, such as proliferation-accelerating and anti-apoptosis effects on cancer progression.
|
29370558 |
2018 |
|
Neoplasm Metastasis
|
0.060 |
Biomarker
|
phenotype |
BEFREE |
PIM3 Functions as Oncogenic Factor and Promotes the Tumor Growth and Metastasis in Colorectal Cancer.
|
30417983 |
2019 |
|
Malignant neoplasm of colon and/or rectum
|
0.020 |
Biomarker
|
disease |
BEFREE |
PIM3 Functions as Oncogenic Factor and Promotes the Tumor Growth and Metastasis in Colorectal Cancer.
|
30417983 |
2019 |
|
Carcinogenesis
|
0.070 |
AlteredExpression
|
phenotype |
BEFREE |
PIM3 expression plays a role in hepatoblastoma tumorigenesis.
|
30898394 |
2019 |
|
Hepatoblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
PIM3 warrants investigation as a therapeutic target and prognostic marker for hepatoblastoma.
|
30898394 |
2019 |
|
leukemia
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
PIM3 overexpression rescued the anti-proliferative effect observed with PIM3 knockdown.
|
30898394 |
2019 |