MC4R, melanocortin 4 receptor, 4160

N. diseases: 149; N. variants: 58
Disease: Attention deficit hyperactivity disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1263846
Disease: Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder 		0.040 GeneticVariation disease BEFREE We hope that our paper will stimulate further studies testing if the early screening for ADHD symptoms and their appropriate treatment may be an effective way to prevent obesity in a subset of children with MC4R mutation. 25466298 2015
CUI: C1263846
Disease: Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder 		0.040 GeneticVariation disease BEFREE Atomoxetine proved to efficiently reduce weight in a severely obese MC4R mutation carrier with ADHD. 23493066 2013
CUI: C1263846
Disease: Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder 		0.040 GeneticVariation disease BEFREE Successful methylphenidate treatment of early onset extreme obesity in a child with a melanocortin-4 receptor gene mutation and attention deficit/hyperactivity disorder. 21211528 2011
CUI: C1263846
Disease: Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder 		0.040 GeneticVariation disease BEFREE We conclude that in our sample, the MC4R (C271R) mutation causing obesity, is in association with ADHD. 18777518 2008