CD46, CD46 molecule, 4179

N. diseases: 258; N. variants: 21
Disease: Neuroblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 AlteredExpression disease BEFREE ASK1 (MAP3K5) and TLX expression are both enhanced in SP (side population) NB and patient-derived primary NB sphere cell lines, but the majority of non-SP NB lines express lower ASK1 expression. 27890558 2017
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 AlteredExpression disease BEFREE Further, the Kaplan-Meier estimator indicated a negative correlation between TLX expression and survival in 88 NB patients. 25356871 2014
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 Biomarker disease BEFREE In summary, MV-CEA has potent therapeutic efficacy against NB mediated by a CD46- and nectin 4-independent pathway. 22796607 2012
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 Biomarker disease BEFREE Compared to parental vaccine strain, Edmonston (Ed) MV, both had normal growth and cytopathic effects in Vero cells and showed similar growth kinetics in human neuroblastoma SK-N-MC cells and in primary mouse neurons expressing the MV receptor, CD46. 10648185 2000
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 AlteredExpression disease BEFREE Neuroblastoma expressed regulators MCP and CD59 but did not express DAF or CR1. 8964911 1996