CD46, CD46 molecule, 4179

N. diseases: 258; N. variants: 21
Disease: Adenoviral infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0851887
Disease: Adenoviral infections
Adenoviral infections 		0.030 AlteredExpression group BEFREE The results showed that this modification in fiber region facilitates adenoviral infection to bladder cancer, perhaps due to high expression of CD46 on target cell surface. 21437625 2011
CUI: C0851887
Disease: Adenoviral infections
Adenoviral infections 		0.030 Biomarker group BEFREE We have previously shown that coxsackie-adenovirus receptor (CAR) is expressed at decreased levels in several primary head and neck squamous cell carcinoma (HNSCC) cell lines established from tumor samples and that retargeting adenoviral infection to the CD46 receptor using the Ad5/35 hybrid virus results in highly efficient transfection of these cells. 19082458 2009
CUI: C0851887
Disease: Adenoviral infections
Adenoviral infections 		0.030 Biomarker group BEFREE At the same time, blocking the CD46 receptor caused a 65% inhibition of adenoviral infection when using Ad5/3. 16716112 2006