CD46, CD46 molecule, 4179

N. diseases: 258; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 AlteredExpression disease BEFREE We found that the levels of CD46 expression in HCC tissues were significantly higher compared to that in the adjacent normal tissues. 24297460 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 AlteredExpression disease BEFREE Thus, we conclude that HBx contributes to the protection of hepatoma and hepatic cells from CDC by up-regulation of CD46. 23391762 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 AlteredExpression disease BEFREE In this study we showed that all HCC cell lines and clinical samples expressed high level of CD46, the receptor for Adenovirus 35 (Ad35) and constructed new fiber chimeric oncolytic adenoviruses with or without a p53 gene expression cassette, SG635-p53 and SG635, respectively. 21504839 2011
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 AlteredExpression disease BEFREE The CD46 receptor was highly expressed in HCC compared to nonmalignant hepatic tissue. 17133484 2006