MDK, midkine, 4192

N. diseases: 209; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.040 Biomarker disease BEFREE If MK2 level increased, it would be 5.030 likely to had metastases.Our results indicated that MK could potentially be used as a disease monitoring biomarker for PTC, although inferior to Tg. 30200153 2018
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.040 AlteredExpression disease BEFREE In conclusion, our results suggest that midkine expression could be a clinically useful marker in predicting the presence of multiple lymph node metastases in BRAFV600E PTC. 26297257 2015
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.040 AlteredExpression disease BEFREE The expression level of MK in PTC with BRAF mutation was significantly higher than that in PTC with wild-type BRAF (P < 0.001). 24272599 2014
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.040 AlteredExpression disease BEFREE We conclude that thyroid papillary carcinoma strongly expresses MK protein and messenger RNA, and that this overexpression may relate to the development and invasion of these carcinomas. 11048798 2000