MDK, midkine, 4192

N. diseases: 209; N. variants: 1
Disease: Childhood Kidney Wilms Tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1333015
Disease: Childhood Kidney Wilms Tumor
Childhood Kidney Wilms Tumor 		0.040 Biomarker disease BEFREE On the basis of these findings, we conclude that the MK promoter is a candidate tumor-specific promoter for Wilms' tumor or neuroblastoma. 10969765 2000
CUI: C1333015
Disease: Childhood Kidney Wilms Tumor
Childhood Kidney Wilms Tumor 		0.040 PosttranslationalModification disease BEFREE Midkine stimulates Wilms' tumor cell proliferation via its signaling receptor. 9193798 1997
CUI: C1333015
Disease: Childhood Kidney Wilms Tumor
Childhood Kidney Wilms Tumor 		0.040 AlteredExpression disease BEFREE The high expression level of MK in all Wilms' tumor specimens so far examined and the presence of two WT1 elements (5'-GCGGGGGCG-3') in the human MK promoter region led us to examine the possible role of the WT1 gene product in the regulation of MK gene expression. 8950987 1996
CUI: C1333015
Disease: Childhood Kidney Wilms Tumor
Childhood Kidney Wilms Tumor 		0.040 AlteredExpression disease BEFREE All of 6 surgically removed specimens of Wilms' tumor highly expressed MK. 8383007 1993